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The iScreen™ Urine Test Dx Drug Screen Cup utilizes lateral flow chromatographic immunoassay technology to detect specific drugs and their metabolites in human urine. After the urine specimen is collected directly into the cup, the sample migrates through multiple test strips containing highly specific antibodies for each targeted drug analyte.
If the concentration of a drug is below its designated screening cutoff level, two colored lines appear—one in the Control (C) region and one in the Test (T) region—indicating a negative result. If the concentration is at or above the cutoff level, only the Control (C) line appears, indicating a preliminary positive result.
At the same time, the integrated Specimen Validity Testing (SVT) evaluates important urine characteristics such as Creatinine (CR), pH, and Oxidants (OX) to help identify diluted or adulterated urine specimens before interpreting the screening results.
Because this is a preliminary screening test, any preliminary positive result should be confirmed using a laboratory-based confirmatory method such as Gas Chromatography/Mass Spectrometry (GC-MS) or Liquid Chromatography–Mass Spectrometry (LC-MS/MS)
Amphetamine is a powerful central nervous system (CNS) stimulant commonly prescribed to treat Attention Deficit Hyperactivity Disorder (ADHD) and narcolepsy. When used under medical supervision, it helps improve focus, concentration, and alertness. However, amphetamine is also widely abused for its stimulating and euphoric effects, making it one of the most commonly detected drugs in workplace, clinical, and forensic drug testing programs.
People misuse amphetamines by swallowing tablets, snorting crushed pills, smoking, or injecting the drug. Repeated misuse can lead to physical dependence, psychological addiction, cardiovascular complications, and mental health disorders.
Increased energy and alertness
Euphoria
Increased heart rate
Elevated blood pressure
Reduced appetite
Restlessness
Long-term misuse may lead to aggression, paranoia, heart disease, severe weight loss, and substance dependence.
Speed, Uppers, Bennies, Black Beauties, Pep Pills, Dexies, Addys.
Amphetamine is generally detectable in urine for 1–3 days after use, although heavy or chronic use may extend the detection period
Barbiturates are a class of central nervous system depressants used to treat conditions such as seizure disorders, insomnia, anxiety, and for anesthesia induction. Although their medical use has declined due to the availability of safer medications, some barbiturates are still prescribed for specific medical conditions.
Because they slow brain activity, barbiturates have a high potential for misuse and dependence. Taking barbiturates in excessive doses or combining them with alcohol or opioids can significantly increase the risk of respiratory depression, overdose, and death.
Relaxation
Drowsiness
Sedation
Slowed breathing
Impaired coordination
Slurred speech
Confusion
Dizziness
Long-term misuse may result in tolerance, dependence, withdrawal symptoms, respiratory failure, and overdose.
Barbs, Downers, Reds, Blues, Yellow Jackets, Rainbows.
Barbiturates may remain detectable in urine for 2–15 days, depending on the specific medication and duration of use
Buprenorphine is a partial opioid agonist primarily prescribed to treat opioid use disorder (OUD) and, in some cases, chronic pain. It helps reduce opioid cravings and withdrawal symptoms while producing a lower risk of respiratory depression than full opioid agonists.
Although buprenorphine is an important medication in addiction treatment programs, it may also be misused or diverted for non-medical purposes. As a result, it is commonly included in workplace, rehabilitation, and clinical drug testing panels.
Pain relief
Relaxation
Reduced opioid cravings
Drowsiness
Dizziness
Nausea
Constipation
Slowed breathing
Improper use or combining buprenorphine with alcohol or other depressants may increase the risk of overdose and respiratory failure.
Bupe, Subs, Suboxone, Subutex, Orange Stops.
Buprenorphine is generally detectable in urine for 3–7 days after the last use, although chronic users may remain positive for a longer period
Benzodiazepines are prescription central nervous system depressants commonly used to treat anxiety disorders, panic attacks, insomnia, muscle spasms, and seizure disorders. They work by enhancing the effects of gamma-aminobutyric acid (GABA), a neurotransmitter that slows activity in the brain and produces a calming effect.
While highly effective when used appropriately, benzodiazepines carry a significant risk of tolerance, dependence, and misuse. They are among the most frequently monitored prescription medications in workplace, rehabilitation, and clinical drug screening programs.
Calmness
Relaxation
Reduced anxiety
Drowsiness
Muscle relaxation
Impaired coordination
Slowed reaction time
Memory impairment
Long-term misuse may lead to physical dependence, withdrawal symptoms, cognitive impairment, and an increased risk of overdose, especially when combined with opioids or alcohol.
Benzos, Xannies, Bars, Vallies, Tranks, Downers.
Benzodiazepines are typically detectable in urine for 2–7 days, although long-acting benzodiazepines may remain detectable for several weeks in chronic users
Cocaine is a powerful central nervous system stimulant derived from the leaves of the coca plant. Although it has limited medical use in certain specialized procedures, it is primarily known as an illicit drug with a high potential for abuse and addiction. Cocaine produces an intense but short-lived feeling of euphoria by increasing dopamine levels in the brain, often leading users to take repeated doses.
People commonly use cocaine by snorting, smoking crack cocaine, or injecting it intravenously. Repeated use can rapidly lead to physical and psychological dependence. Because cocaine affects both the cardiovascular and nervous systems, even occasional misuse can pose serious health risks.
Increased energy and alertness
Euphoria and overconfidence
Rapid heart rate
Elevated blood pressure
Decreased appetite
Anxiety
Restlessness
Strong drug cravings
Long-term abuse may increase the risk of heart attack, stroke, depression, memory problems, and substance use disorder.
Coke, Blow, Snow, Crack, Rock, Flake, Yayo, Nose Candy, White, Dust.
Cocaine metabolites are typically detectable in urine for 2–4 days after occasional use, although chronic or heavy users may remain positive for a longer period
Fentanyl is a synthetic opioid analgesic that is approximately 50 to 100 times more potent than morphine. It is prescribed for the management of severe pain, particularly after surgery or in patients with advanced cancer. Due to its extreme potency, fentanyl has become one of the leading causes of opioid overdose deaths when obtained or used illegally.
Illicitly manufactured fentanyl is frequently mixed with heroin, cocaine, methamphetamine, and counterfeit prescription medications, often without the user's knowledge. Even very small amounts can produce life-threatening respiratory depression.
Powerful pain relief
Euphoria
Extreme drowsiness
Slowed breathing
Pinpoint pupils
Confusion
Sedation
Loss of consciousness
Misuse can rapidly lead to overdose, respiratory failure, coma, and death.
Apache, China White, Dance Fever, Jackpot, TNT, Goodfellas, Tango & Cash.
Fentanyl is generally detectable in urine for 1–3 days after use, although prolonged or heavy use may extend the detection period
MDMA (3,4-Methylenedioxymethamphetamine), commonly known as Ecstasy or Molly, is a synthetic psychoactive drug with both stimulant and mild hallucinogenic properties. It increases the release of serotonin, dopamine, and norepinephrine, producing feelings of euphoria, emotional closeness, increased energy, and enhanced sensory perception.
MDMA is frequently abused at parties, music festivals, concerts, and nightclubs. Although users often associate it with recreational settings, repeated or high-dose use can lead to dehydration, hyperthermia, cardiovascular complications, and long-term effects on brain function.
Euphoria
Increased energy
Emotional warmth
Enhanced sensory perception
Increased heart rate
Jaw clenching
Sweating
Dehydration
Long-term misuse may contribute to anxiety, depression, memory problems, sleep disturbances, and cognitive impairment.
Ecstasy, Molly, X, E, Beans, Adam, Love Drug, Rolls.
MDMA is generally detectable in urine for 2–4 days after use, although heavy or repeated use may extend the detection period.
Methamphetamine is a highly addictive central nervous system stimulant that affects the brain and nervous system. Although it has limited prescription use for certain medical conditions, it is primarily known as an illicit drug with a high potential for abuse and addiction. Methamphetamine rapidly increases dopamine levels in the brain, producing intense feelings of euphoria, increased energy, and heightened alertness.
People commonly abuse methamphetamine by smoking, snorting, swallowing, or injecting it. Repeated use can quickly lead to physical dependence, severe psychological addiction, and long-term damage to the brain, heart, and other organs.
Intense euphoria
Increased energy
Heightened alertness
Rapid heartbeat
Elevated blood pressure
Decreased appetite
Anxiety
Aggressive behavior
Long-term abuse may result in severe weight loss, memory impairment, paranoia, hallucinations, dental problems ("meth mouth"), and permanent brain damage.
Meth, Crystal Meth, Crystal, Ice, Glass, Tina, Speed.
Methamphetamine is typically detectable in urine for 2–4 days after use, although heavy or chronic users may remain positive for a longer period
Opiates are a group of drugs naturally derived from the opium poppy, including morphine and codeine, as well as related substances detected through opioid screening. They are commonly prescribed to relieve moderate to severe pain but are also widely abused because of their powerful pain-relieving and euphoric effects.
Misuse of opiates can rapidly lead to tolerance, dependence, addiction, and life-threatening respiratory depression. Opiates are among the most commonly screened substances in workplace, clinical, and rehabilitation drug testing programs.
Pain relief
Euphoria
Relaxation
Opiates are a group of drugs naturally derived from the opium poppy, including morphine and codeine, as well as related substances detected through opioid screening. They are commonly prescribed to relieve moderate to severe pain but are also widely abused because of their powerful pain-relieving and euphoric effects.
Misuse of opiates can rapidly lead to tolerance, dependence, addiction, and life-threatening respiratory depression. Opiates are among the most commonly screened substances in workplace, clinical, and rehabilitation drug testing programs.
Pain relief
Euphoria
Relaxation
Drowsiness
Constricted pupils
Slowed breathing
Nausea
Constipation
Long-term misuse may cause opioid dependence, overdose, respiratory failure, coma, and death.
Smack, Dope, H, Junk, Horse, Mud, Big O.
Opiates are generally detectable in urine for 2–3 days after use, depending on the specific opioid and frequency of use
Opiates are a group of drugs naturally derived from the opium poppy, including morphine and codeine, as well as related substances detected through opioid screening. They are commonly prescribed to relieve moderate to severe pain but are also widely abused because of their powerful pain-relieving and euphoric effects.
Misuse of opiates can rapidly lead to tolerance, dependence, addiction, and life-threatening respiratory depression. Opiates are among the most commonly screened substances in workplace, clinical, and rehabilitation drug testing programs.
Pain relief
Euphoria
Relaxation
Drowsiness
Constricted pupils
Slowed breathing
Nausea
Constipation
Long-term misuse may cause opioid dependence, overdose, respiratory failure, coma, and death.
Smack, Dope, H, Junk, Horse, Mud, Big O.
Opiates are generally detectable in urine for 2–3 days after use, depending on the specific opioid and frequency of use
Methadone is a long-acting synthetic opioid prescribed to treat chronic pain and opioid use disorder. It helps reduce opioid withdrawal symptoms and cravings by acting on the same opioid receptors as drugs such as heroin and morphine, but with a much longer duration of action.
Although methadone is an effective medication when used under medical supervision, it can also be misused and may cause serious side effects if taken improperly. Because of its potential for abuse, methadone is frequently included in comprehensive drug testing panels.
Pain relief
Reduced opioid cravings
Relaxation
Drowsiness
Slowed breathing
Sweating
Nausea
Dizziness
Improper use may result in overdose, respiratory depression, irregular heartbeat, and dependence.
Fizzies, Dollies, Juice, Amidone, Methadose.
Methadone is typically detectable in urine for 3–7 days, although frequent use may extend the detection window
Oxycodone is a prescription opioid pain medication used to treat moderate to severe pain. While highly effective when taken as prescribed, oxycodone also has a significant potential for misuse because it produces feelings of relaxation and euphoria.
Repeated misuse may lead to tolerance, physical dependence, addiction, and overdose. Oxycodone is commonly included in workplace, healthcare, and pain management drug testing panels.
Pain relief
Relaxation
Euphoria
Drowsiness
Slowed breathing
Constricted pupils
Nausea
Constipation
Long-term misuse increases the risk of dependence, overdose, respiratory failure, and death.
Oxy, Hillbilly Heroin, OC, Roxies, Percs, Blues.
Oxycodone is generally detectable in urine for 2–4 days after use
Phencyclidine (PCP), commonly known as Angel Dust, is a dissociative anesthetic that was originally developed for medical use but later discontinued because of its severe psychological side effects. Today, PCP is an illegal drug abused for its hallucinogenic and dissociative properties.
PCP can significantly alter perception, mood, and behavior, sometimes causing violent or unpredictable actions. Because of these risks, PCP is routinely included in multi-panel drug testing.
Hallucinations
Detachment from reality
Oxy, Hillbilly Heroin, OC, Roxies, Percs, Blues.
Oxycodone is generally detectable in urine for 2–4 days after use
Phencyclidine (PCP), commonly known as Angel Dust, is a dissociative anesthetic that was originally developed for medical use but later discontinued because of its severe psychological side effects. Today, PCP is an illegal drug abused for its hallucinogenic and dissociative properties.
PCP can significantly alter perception, mood, and behavior, sometimes causing violent or unpredictable actions. Because of these risks, PCP is routinely included in multi-panel drug testing.
Hallucinations
Detachment from reality
Numbness
Agitation
Confusion
Aggressive behavior
Loss of coordination
Elevated blood pressure
Heavy use may lead to psychosis, seizures, coma, or death.
Angel Dust, Rocket Fuel, Sherm, Wet, Embalming Fluid, Love Boat.
PCP is generally detectable in urine for 5–8 days, although chronic users may remain positive for several weeks
Numbness
Agitation
Confusion
Aggressive behavior
Loss of coordination
Elevated blood pressure
Heavy use may lead to psychosis, seizures, coma, or death.
Angel Dust, Rocket Fuel, Sherm, Wet, Embalming Fluid, Love Boat.
PCP is generally detectable in urine for 5–8 days, although chronic users may remain positive for several weeks
Tricyclic antidepressants (TCAs) are prescription medications used to treat depression, certain anxiety disorders, chronic nerve pain, and migraine prevention. Although they are effective medications when used correctly, overdose or misuse can produce serious cardiovascular and neurological complications.
Drug testing for TCAs is often performed in emergency medicine, pain management, and overdose investigations to help identify recent exposure.
Improved mood
Drowsiness
Dry mouth
Blurred vision
Constipation
Dizziness
Increased heart rate
Difficulty concentrating
Excessive doses may cause seizures, irregular heartbeat, confusion, or coma.
TCAs generally do not have widely recognized street names because they are prescription medications.
Tricyclic antidepressants are typically detectable in urine for 2–7 days, depending on the specific medication and duration of use
Marijuana is a psychoactive drug derived from the Cannabis sativa plant. Its primary active compound, Delta-9-tetrahydrocannabinol (THC), affects the brain by interacting with cannabinoid receptors, producing feelings of relaxation, altered perception, and euphoria.
Marijuana may be smoked, vaporized, or consumed in edible products. Although legalized for medical or recreational use in some regions, THC remains one of the most commonly tested substances in workplace, clinical, and forensic drug screening programs.
Relaxation
Euphoria
Altered perception
Increased appetite
Dry mouth
Red eyes
Slowed reaction time
Impaired coordination
Frequent or heavy use may contribute to memory impairment, anxiety, reduced concentration, and cannabis dependence.
Weed, Marijuana, Pot, Cannabis, Grass, Herb, Ganja, Mary Jane, Hash.
THC detection varies depending on frequency of use. It is typically detectable in urine for 3–30 days, with chronic users remaining positive for several weeks
The integrated Specimen Validity Testing (SVT) helps determine whether the urine specimen has been diluted, substituted, or adulterated before interpreting the drug screening results.
This configuration evaluates:
Creatinine (CR) – Helps identify diluted urine specimens.
pH – Detects unusually acidic or alkaline urine.
Oxidants (OX) – Detects oxidizing adulterants that may interfere with drug testing.
SVT provides additional confidence that the specimen is suitable for accurate preliminary drug screening
The iScreen™ Urine Test Dx Drug Screen Cup (14 Panel + SVT) provides a fast, reliable, and convenient solution for preliminary multi-drug screening from a single urine specimen. By detecting 14 commonly abused drugs, including Fentanyl, and incorporating Specimen Validity Testing (SVT), it helps improve confidence in screening results while reducing specimen handling. With results available in approximately 5 minutes, the self-contained collection cup is well suited for clinical, occupational, forensic, and rehabilitation settings. As with all rapid immunoassay screening devices, any preliminary positive result should be confirmed using GC-MS or LC-MS/MS before medical, legal, or employment decisions are made.
The iScreen™ Urine Test Dx Drug Screen Cup is a CLIA-waived, self-contained multi-panel urine drug screening device designed to provide fast, accurate, and reliable preliminary detection of multiple drugs of abuse from a single urine specimen. Combining specimen collection and testing into one convenient device, the iScreen™ Dx Cup minimizes specimen handling and reduces exposure during the collection process, making it an ideal solution for professional point-of-care drug testing.
This iScreen™ Urine Test Dx14-panel urine drug test cup screens for 14 commonly abused drugs, including Fentanyl (FTY), one of the most significant synthetic opioids involved in today's opioid crisis. In addition to drug screening, the cup also incorporates Specimen Validity Testing (SVT), allowing users to verify specimen integrity by checking for possible dilution or adulteration before interpreting the drug test results.
Using advanced lateral flow immunoassay technology, the iScreen™ Dx Cup provides qualitative preliminary results in approximately 5 minutes without the need for additional laboratory equipment. The device is designed for use in hospitals, physician offices, clinical laboratories, occupational health clinics, rehabilitation centers, correctional facilities, workplace drug testing programs, and other professional healthcare environments.
Available in both round and square cup formats, the iScreen™ Dx Cup offers a simple, hygienic, and efficient method of urine drug screening while maintaining high standards of accuracy and ease of use
This 14 Panel + Specimen Validity Testing (SVT) configuration screens for the following drug analytes:
This configuration also evaluates urine specimen integrity by testing:
Drug
Typical Detection Window
Amphetamine (AMP)
1–3 Days
Barbiturates (BAR)
2–15 Days
Buprenorphine (BUP)
3–7 Days
Benzodiazepines (BZO)
2–7 Days*
Cocaine (COC)
2–4 Days
Fentanyl (FTY)
1–3 Days
MDMA
2–4 Days
Methamphetamine (MET)
2–4 Days
Opiates (OPI)
2–3 Days
Methadone (MTD)
3–7 Days
Oxycodone (OXY)
2–4 Days
PCP
5–8 Days
TCA
2–7 Days
THC
3–30 Days
*Long-acting benzodiazepines may remain detectable longer
A colored line appears in the Control (C) region and another colored line appears in the Test (T) region for each drug being tested. Even a faint Test (T) line should be interpreted as a negative result.
Only the Control (C) line appears, while no Test (T) line is visible for the corresponding drug. This indicates that the drug concentration may be at or above the screening cutoff level. All preliminary positive results should be confirmed using Gas Chromatography/Mass Spectrometry (GC-MS) or Liquid Chromatography–Mass Spectrometry (LC-MS/MS).
If the Control (C) line does not appear, the test is invalid regardless of whether a Test line appears. Repeat the test using a new device and a fresh urine specimen

iScreen™ Urine Test Dx Drug Screen Cup CLIA-Waived | Abbott | AMP, BAR, BUP, BZO, COC, FTY, MDMA, MET, MOP/OPI, MTD, OXY, PCP, TCA, THC | ABTDUAW114705E 25/Box
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