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The iScreen™ Cube Oral Fluid Drug Screen Test uses lateral flow chromatographic immunoassay technology to detect drugs and their metabolites in human oral fluid. The collection swab is placed inside the mouth until the sample saturation indicator confirms that a sufficient amount of saliva has been collected. The swab is then inserted into the testing device, where the oral fluid migrates across individual test membranes containing antibodies specific to each targeted drug.
If the drug concentration is below the established screening cutoff level, both the Control (C) and Test (T) lines appear, indicating a negative result. If the drug concentration is equal to or greater than the cutoff level, only the Control (C) line appears, indicating a preliminary positive result.
Because this device provides only preliminary screening results, any positive finding should be confirmed using Gas Chromatography/Mass Spectrometry (GC-MS), Liquid Chromatography/Mass Spectrometry (LC-MS), or equivalent confirmatory laboratory methods before making medical, legal, or employment decisions
Amphetamine is a prescription central nervous system (CNS) stimulant commonly used to treat Attention Deficit Hyperactivity Disorder (ADHD) and narcolepsy. It works by increasing certain neurotransmitters in the brain, helping improve focus, attention, and alertness. However, amphetamine is also frequently misused because of its stimulating and performance-enhancing effects.
Due to its abuse potential, amphetamine is routinely included in workplace, clinical, forensic, and rehabilitation drug testing programs.
Increased energy
Improved alertness
Elevated mood
Increased heart rate
Reduced appetite
Restlessness
Anxiety
Insomnia
Long-term misuse may result in dependence, cardiovascular complications, aggression, and mental health disorders.
Speed, Uppers, Bennies, Dexies, Pep Pills, Addys.
Amphetamine is generally detectable in oral fluid for approximately 24–48 hours after use
Barbiturates are medications that depress the central nervous system and are prescribed to treat seizure disorders, anxiety, insomnia, and for anesthesia during certain medical procedures. Although less commonly prescribed today, barbiturates still carry a significant risk of misuse and overdose.
Because of their sedative effects, they remain an important component of comprehensive drug screening programs.
Relaxation
Sedation
Drowsiness
Slowed breathing
Poor coordination
Slurred speech
Dizziness
Confusion
Long-term misuse may lead to dependence, respiratory depression, and overdose.
Barbs, Downers, Reds, Blues, Yellow Jackets, Rainbows.
Barbiturates are generally detectable in oral fluid for approximately 1–2 days, depending on the specific medication
Cocaine is a powerful central nervous system stimulant derived from the coca plant. It produces intense but short-lived feelings of euphoria, increased confidence, and energy by rapidly increasing dopamine levels in the brain. Cocaine has a high potential for abuse and addiction and is routinely included in workplace, clinical, and forensic drug testing panels.
Increased energy
Euphoria
Heightened alertness
Rapid heartbeat
Elevated blood pressure
Reduced appetite
Anxiety
Restlessness
Coke, Blow, Snow, Crack, Rock, Flake, Yayo, White, Dust.
Cocaine is generally detectable in oral fluid for approximately 24–48 hours after use
MDMA (3,4-Methylenedioxymethamphetamine), commonly known as Ecstasy or Molly, is a synthetic psychoactive drug with stimulant and mild hallucinogenic properties. It increases serotonin, dopamine, and norepinephrine levels in the brain, producing feelings of euphoria, emotional warmth, and increased energy.
Although commonly associated with parties and music festivals, repeated use may lead to dehydration, hyperthermia, cardiovascular complications, and long-term cognitive impairment.
Euphoria
Increased energy
Emotional warmth
Enhanced sensory perception
Increased heart rate
Jaw clenching
Sweating
Dehydration
Long-term misuse may contribute to anxiety, depression, sleep disturbances, and memory problems.
Ecstasy, Molly, X, E, Beans, Adam, Love Drug, Rolls.
MDMA is generally detectable in oral fluid for approximately 24–48 hours after use
Methamphetamine is a highly addictive synthetic stimulant that affects the brain and central nervous system. It produces intense feelings of euphoria, increased energy, and heightened
alertness. Because of its powerful stimulant effects, methamphetamine has a high risk of abuse and long-term addiction.
Intense euphoria
Increased energy
Heightened alertness
Rapid heartbeat
Elevated blood pressure
Reduced appetite
Anxiety
Aggressive behavior
Long-term misuse may result in severe weight loss, hallucinations, paranoia, memory impairment, and permanent brain damage.
Meth, Crystal Meth, Ice, Glass, Tina, Crank.
Methamphetamine is generally detectable in oral fluid for approximately 24–72 hours after use.
Methadone is a long-acting synthetic opioid prescribed for the treatment of chronic pain and opioid use disorder. It is commonly used in medication-assisted treatment (MAT) programs to reduce opioid withdrawal symptoms and cravings. While highly effective when used under medical supervision, methadone also has the potential for misuse, dependence, and overdose.
Because of its abuse potential, methadone is routinely included in workplace, clinical, and rehabilitation drug testing panels.
Pain relief
Relaxation
Reduced opioid cravings
Drowsiness
Slowed breathing
Sweating
Dizziness
Nausea
Long-term misuse may result in dependence, respiratory depression, irregular heartbeat, overdose, and death.
Fizzies, Dollies, Juice, Amidone, Methadose.
Methadone is generally detectable in oral fluid for approximately 24–48 hours after use
Opiates are naturally occurring opioid drugs derived from the opium poppy, including morphine and codeine. They are commonly prescribed to relieve moderate to severe pain but are also frequently abused because of their pain-relieving and euphoric effects.
Repeated misuse can quickly lead to tolerance, physical dependence, addiction, and life-threatening respiratory depression.
Pain relief
Euphoria
Relaxation
Drowsiness
Constricted pupils
Slowed breathing
Nausea
Constipation
Long-term misuse may result in opioid dependence, overdose, respiratory failure, coma, and death.
Smack, Dope, H, Horse, Junk, Mud, Big O.
Opiates are generally detectable in oral fluid for approximately 24–48 hours after use
Oxycodone is a semi-synthetic opioid analgesic prescribed to treat moderate to severe pain. While highly effective for pain management, it also carries a significant risk of misuse, dependence, and addiction due to its euphoric effects.
Because oxycodone is one of the most commonly misused prescription opioids, many professional drug screening programs include a dedicated test for this drug.
Pain relief
Euphoria
Drowsiness
Relaxation
Slowed breathing
Dizziness
Nausea
Constipation
Long-term misuse may lead to opioid dependence, overdose, respiratory depression, and death.
Oxy, OCs, Percs, Hillbilly Heroin, Roxies.
Oxycodone is generally detectable in oral fluid for approximately 24–48 hours after use
Phencyclidine (PCP), commonly known as Angel Dust, is a dissociative hallucinogenic drug originally developed as an anesthetic. Although its medical use has been discontinued, PCP continues to be abused because of its powerful hallucinogenic and mind-altering effects.
Hallucinations
Detachment from reality
Confusion
Aggressive behavior
Numbness
Loss of coordination
Elevated blood pressure
Agitation
Heavy use may result in seizures, psychosis, coma, or death.
Angel Dust, Sherm, Wet, Rocket Fuel, Love Boat, Embalming Fluid.
PCP is generally detectable in oral fluid for approximately 24–72 hours after use
Marijuana is a psychoactive substance obtained from the Cannabis sativa plant. Its primary active ingredient, Delta-9-tetrahydrocannabinol (THC), produces feelings of relaxation, altered perception, and euphoria.
Because oral fluid testing detects recent drug exposure, it is particularly useful for identifying recent marijuana use.
Relaxation
Euphoria
Altered perception
Increased appetite
Dry mouth
Red eyes
Slowed reaction time
Impaired coordination
Frequent or heavy use may contribute to memory impairment, anxiety, reduced concentration, and cannabis dependence.
Weed, Pot, Cannabis, Grass, Herb, Ganja, Mary Jane, Hash.
THC is generally detectable in oral fluid for approximately 12–24 hours after use, although frequent users may remain positive for a longer period
The iScreen™ Cube Oral Fluid Drug Screen Test (10 Panel) provides a fast, reliable, and non-invasive solution for the preliminary detection of 10 commonly abused drugs using oral fluid. Its integrated sample collection swab, built-in saturation indicator, secure tamper-resistant design, and easy-to-read results make it ideal for professional drug screening in workplace, healthcare, rehabilitation, forensic, and occupational health settings.
With results available in approximately 10 minutes, the iScreen™ Cube simplifies specimen collection while helping reduce opportunities for specimen substitution or adulteration. As with all rapid immunoassay screening devices, any preliminary positive result should be confirmed using Gas Chromatography/Mass Spectrometry (GC-MS), Liquid Chromatography/Mass Spectrometry (LC-MS), or equivalent confirmatory laboratory methods before medical, legal, or employment decisions are made.
The iScreen™ Cube Oral Fluid Drug Screen Test is a rapid, non-invasive oral fluid screening device designed for the qualitative detection of 10 commonly abused drugs in human saliva. Using advanced lateral flow chromatographic immunoassay technology, the test provides fast and reliable preliminary results in approximately 10 minutes, making it ideal for professional point-of-care drug testing.
Unlike traditional urine drug tests, the iScreen™ Cube uses oral fluid (saliva) as the testing specimen, eliminating the need for urine collection while reducing opportunities for specimen substitution, adulteration, and tampering. The integrated collection swab includes a sample saturation indicator, ensuring that an adequate oral fluid specimen has been collected before testing begins.
The device features a secure locking lid with an integrated clip, helping maintain specimen integrity throughout the testing process. Its compact, self-contained design combines specimen collection and drug screening into a single device, allowing for easy administration and interpretation of results. The photocopiable result window also simplifies documentation and record keeping.
The iScreen™ Cube is available in 5 to 10 drug panel configurations, allowing organizations to select the panel that best suits their testing requirements. This 10-panel configuration simultaneously screens for multiple commonly abused drugs from a single oral fluid specimen.
This assay provides preliminary qualitative screening results only. Any preliminary positive result should be confirmed using a more specific analytical technique such as Gas Chromatography/Mass Spectrometry (GC-MS), Liquid Chromatography/Mass Spectrometry (LC-MS), or their tandem mass spectrometry methods before medical, legal, or employment decisions are made.
The iScreen™ Cube Oral Fluid Drug Screen Test is intended for professional use only and is not intended for clinical diagnosis
This 10 Panel configuration screens for:
Drug
Typical Oral Fluid Detection Window
Amphetamine (AMP)
24–48 Hours
Barbiturates (BAR)
1–2 Days
Cocaine (COC)
24–48 Hours
MDMA
24–48 Hours
Methamphetamine (MET)
24–72 Hours
Methadone (MTD)
24–48 Hours
Opiates (OPI)
24–48 Hours
Oxycodone (OXY)
24–48 Hours
Phencyclidine (PCP)
24–72 Hours
Marijuana (THC)
12–24 Hours*
*Detection windows may vary depending on frequency of use, dosage, metabolism, and individual physiology
A colored line appears in both the Control (C) region and the Test (T) region for each drug panel. Even a faint Test (T) line should be interpreted as a negative result, indicating that the drug concentration is below the established screening cutoff level.
Only one colored line appears in the Control (C) region while no line appears in the corresponding Test (T) region. This indicates that the drug concentration may be at or above the screening cutoff level. Any preliminary positive result should be confirmed using Gas Chromatography/Mass Spectrometry (GC-MS), Liquid Chromatography/Mass Spectrometry (LC-MS), or equivalent confirmatory laboratory methods before medical, legal, or employment decisions are made.
If no colored line appears in the Control (C) region, the test is invalid regardless of whether a Test line appears. Repeat the test using a new device and a new oral fluid specimen
iScreen™ Cube 10 Panel Oral Fluid Drug Screen | Abbott | Amphetamine (AMP) Barbiturates (BAR) Cocaine (COC) MDMA (Ecstasy) Methamphetamine (MET) Methadone (MTD) Opiates (OPI) Oxycodone (OXY) Phencyclidine (PCP) Marijuana (THC) | ABTOFCUBE1001A 25/Box
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