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The iScreen™ Urine Test Dx Drug Screen Cup utilizes lateral flow chromatographic immunoassay technology to detect specific drugs and their metabolites in human urine. After the urine specimen is collected directly into the cup, the sample migrates through individual test strips containing highly specific antibodies for each targeted drug analyte.
If the concentration of a drug is below its designated screening cutoff level, two colored lines appear—one in the Control (C) region and one in the Test (T) region—indicating a negative result. If the concentration is at or above the cutoff level, only the Control (C) line appears, indicating a preliminary positive result.
The device also evaluates Creatinine (CR), pH, and Specific Gravity (SG) to help assess urine specimen integrity and identify abnormal or diluted samples before interpreting the screening results.
As with all rapid immunoassay screening devices, any preliminary positive result should be confirmed using Gas Chromatography/Mass Spectrometry (GC-MS) or Liquid Chromatography–Mass Spectrometry (LC-MS/MS) before medical, legal, or employment decisions are made
Amphetamine is a powerful central nervous system (CNS) stimulant commonly prescribed to treat Attention Deficit Hyperactivity Disorder (ADHD) and narcolepsy. When used under medical supervision, it helps improve attention, concentration, and alertness. However, amphetamine is also widely abused for its stimulating and euphoric effects, making it one of the most frequently detected drugs in workplace and clinical drug testing programs.
Amphetamines may be misused by swallowing tablets, snorting crushed pills, smoking, or injecting the drug. Repeated misuse can lead to physical dependence, psychological addiction, cardiovascular complications, and mental health disorders.
Increased energy and alertness
Elevated mood and euphoria
Increased heart rate
Elevated blood pressure
Reduced appetite
Restlessness
Anxiety
Insomnia
Long-term misuse may lead to aggression, paranoia, severe weight loss, heart disease, and substance dependence.
Speed, Uppers, Bennies, Black Beauties, Pep Pills, Dexies, Addys.
Amphetamine is generally detectable in urine for 1–3 days after use, although chronic or heavy use may extend the detection period
Barbiturates are a class of central nervous system depressants used to treat seizure disorders, insomnia, anxiety, and as anesthetic agents during certain medical procedures. Although their medical use has declined because of safer alternatives, some barbiturates are still prescribed for specific medical conditions.
Because barbiturates slow brain activity, they have a significant potential for misuse and dependence. Taking large doses or combining them with alcohol or opioids greatly increases the risk of respiratory depression and overdose.
Relaxation
Drowsiness
Sedation
Slowed breathing
Impaired coordination
Slurred speech
Confusion
Dizziness
Long-term misuse may result in dependence, withdrawal symptoms, respiratory failure, and overdose.
Barbs, Downers, Reds, Blues, Yellow Jackets, Rainbows.
Barbiturates may remain detectable in urine for 2–15 days, depending on the specific medication and duration of use
Benzodiazepines are prescription medications that act as central nervous system depressants. They are commonly used to treat anxiety disorders, panic attacks, insomnia, muscle spasms, and seizure disorders. These medications work by enhancing the effects of gamma-aminobutyric acid (GABA), producing a calming effect on the brain and nervous system.
Although highly effective when used as prescribed, benzodiazepines carry a significant risk of tolerance, dependence, and misuse. They are among the most commonly monitored prescription medications in workplace, clinical, and rehabilitation drug testing.
Calmness
Relaxation
Reduced anxiety
Drowsiness
Muscle relaxation
Impaired coordination
Slowed reaction time
Memory impairment
Long-term misuse may lead to physical dependence, withdrawal symptoms, cognitive impairment, and increased overdose risk, especially when combined with opioids or alcohol.
Benzos, Xannies, Bars, Vallies, Tranks, Downers.
Benzodiazepines are typically detectable in urine for 2–7 days, although long-acting benzodiazepines may remain detectable for several weeks in chronic users
Buprenorphine is a partial opioid agonist primarily prescribed for the treatment of opioid use disorder (OUD) and, in some cases, chronic pain. It helps reduce opioid cravings and withdrawal symptoms while producing a lower risk of respiratory depression than full opioid agonists.
Although buprenorphine is an important medication in addiction treatment, it may also be misused or diverted for non-medical purposes. As a result, it is commonly included in workplace, rehabilitation, and clinical drug testing panels.
Pain relief
Relaxation
Reduced opioid cravings
Drowsiness
Dizziness
Nausea
Constipation
Slowed breathing
Improper use or combining buprenorphine with alcohol or other depressants may increase the risk of overdose and respiratory failure.
Bupe, Subs, Suboxone, Subutex, Orange Stops.
Buprenorphine is generally detectable in urine for 3–7 days after the last use, although frequent users may remain positive for a longer period
Cocaine is a powerful central nervous system stimulant derived from the leaves of the coca plant. Although it has limited medical use in certain specialized procedures, it is primarily known as an illicit drug with a high potential for abuse and addiction. Cocaine produces an intense but short-lived feeling of euphoria by increasing dopamine levels in the brain, often leading users to take repeated doses.
People commonly use cocaine by snorting, smoking crack cocaine, or injecting it intravenously. Repeated use can rapidly lead to physical and psychological dependence. Because cocaine affects the body's cardiovascular and nervous systems, even occasional misuse can pose significant health risks.
Increased energy and alertness
Euphoria and overconfidence
Rapid heart rate
Elevated blood pressure
Decreased appetite
Anxiety
Restlessness
Strong drug cravings after the effects wear off
Long-term abuse may increase the risk of heart attack, stroke, depression, memory problems, and substance use disorder.
Coke, Blow, Snow, Flake, Crack, Rock, Yayo, Nose Candy, White, Dust.
Cocaine metabolites are typically detectable in urine for 2–4 days after occasional use, although chronic or heavy users may remain positive for a longer period.
Methamphetamine is a highly addictive central nervous system stimulant that affects the brain and nervous system. Although it has limited prescription use for certain medical conditions, it is primarily known as an illicit drug with a very high potential for abuse and addiction. Methamphetamine rapidly increases dopamine levels in the brain, producing intense feelings of euphoria, increased energy, and heightened alertness.
People commonly abuse methamphetamine by smoking, snorting, swallowing, or injecting it. Repeated use can quickly lead to physical dependence, severe psychological addiction, and long-term damage to the brain, heart, and other organs.
Intense euphoria
Increased energy
Heightened alertness
Rapid heartbeat
Elevated blood pressure
Decreased appetite
Anxiety
Aggressive behavior
Long-term abuse may result in severe weight loss, memory impairment, paranoia, hallucinations, dental problems ("meth mouth"), and permanent brain damage.
Meth, Crystal Meth, Crystal, Ice, Glass, Tina, Speed.
Methamphetamine is typically detectable in urine for 2–4 days after use, although heavy or chronic users may remain positive for a longer period.
MDMA (3,4-Methylenedioxymethamphetamine), commonly known as Ecstasy or Molly, is a synthetic psychoactive drug with both stimulant and mild hallucinogenic properties. It increases the release of serotonin, dopamine, and norepinephrine, producing feelings of euphoria, emotional closeness, increased energy, and enhanced sensory perception.
MDMA is frequently abused at parties, music festivals, concerts, and nightclubs. Although users often associate it with recreational settings, repeated or high-dose use can lead to dehydration, hyperthermia, cardiovascular complications, and long-term effects on brain function.
Euphoria
Increased energy
Emotional warmth
Enhanced sensory perception
Increased heart rate
Jaw clenching
Sweating
Dehydration
Long-term misuse may contribute to anxiety, depression, memory problems, sleep disturbances, and cognitive impairment.
Ecstasy, Molly, X, E, Beans, Adam, Love Drug, Rolls.
MDMA is generally detectable in urine for 2–4 days after use, although repeated or heavy use may extend the detection period.
Methadone is a long-acting synthetic opioid prescribed to manage chronic pain and to treat opioid use disorder (OUD) as part of medication-assisted treatment (MAT). It helps reduce opioid cravings and withdrawal symptoms by acting on the same opioid receptors as heroin and morphine but produces a longer-lasting effect.
Although methadone is highly effective when used under medical supervision, it also has the potential for misuse and addiction. Because of its abuse potential, methadone is commonly included in workplace, clinical, and rehabilitation drug testing panels.
Pain relief
Relaxation
Reduced opioid cravings
Drowsiness
Slowed breathing
Sweating
Nausea
Dizziness
Improper use may result in overdose, respiratory depression, irregular heartbeat, dependence, and death.
Fizzies, Dollies, Juice, Amidone, Methadose.
Methadone is generally detectable in urine for 3–7 days, although chronic users may remain positive for a longer period
Opiates are a group of drugs naturally derived from the opium poppy, including morphine and codeine, as well as related opioid compounds. They are commonly prescribed to relieve moderate to severe pain but are also widely abused because of their powerful pain-relieving and euphoric effects.
Repeated misuse of opiates can rapidly lead to tolerance, physical dependence, addiction, and life-threatening respiratory depression. Opiates are among the most frequently screened substances in workplace, healthcare, and rehabilitation drug testing programs.
Pain relief
Euphoria
Relaxation
Drowsiness
Constricted pupils
Slowed breathing
Nausea
Constipation
Long-term misuse
may cause opioid dependence, overdose, respiratory failure, coma, and death.
Smack, Dope, H, Junk, Horse, Mud, Big O.
Opiates are typically detectable in urine for 2–3 days after use, depending on the specific opioid and frequency of use.
Oxycodone is a prescription opioid analgesic used to treat moderate to severe pain. It is commonly prescribed after surgery, injury, or for chronic pain management. While highly effective when taken as directed, oxycodone also has a significant potential for misuse because it produces feelings of relaxation and euphoria.
Repeated misuse may lead to tolerance, physical dependence, addiction, and overdose. Oxycodone is commonly included in workplace, healthcare, and pain management drug testing programs.
Pain relief
Relaxation
Euphoria
Drowsiness
Slowed breathing
Constricted pupils
Nausea
Constipation
Long-term misuse increases the risk of dependence, overdose, respiratory failure, and death.
Oxy, Hillbilly Heroin, OC, Roxies, Percs, Blues.
Oxycodone is generally detectable in urine for 2–4 days after use
Phencyclidine (PCP), commonly known as Angel Dust, is a dissociative anesthetic that was originally developed for medical use but later discontinued because of its severe psychological side effects. Today, PCP is an illegal drug abused for its hallucinogenic and dissociative properties.
PCP can significantly alter perception, mood, and behavior, sometimes causing violent or unpredictable actions. Because of these risks, PCP is routinely included in multi-panel drug testing.
Hallucinations
Detachment from reality
Numbness
Agitation
Confusion
Aggressive behavior
Loss of coordination
Elevated blood pressure
Heavy use may lead to psychosis, seizures, coma, or death.
Angel Dust, Rocket Fuel, Sherm, Wet, Embalming Fluid, Love Boat.
PCP is generally detectable in urine for 5–8 days, although chronic users may remain positive for several weeks
Marijuana is a psychoactive substance derived from the Cannabis sativa plant. Its primary active ingredient, Delta-9-tetrahydrocannabinol (THC), interacts with cannabinoid receptors in the brain to produce feelings of relaxation, euphoria, and altered perception.
Marijuana may be smoked, vaporized, or consumed in edible products. Although legalized for medical or recreational use in some regions, THC remains one of the most commonly screened drugs in workplace, clinical, and forensic drug testing programs.
Relaxation
Euphoria
Altered perception
Increased appetite
Dry mouth
Red eyes
Slowed reaction time
Impaired coordination
Frequent or heavy use may contribute to memory impairment, anxiety, reduced concentration, and cannabis dependence.
Weed, Pot, Cannabis, Grass, Herb, Ganja, Mary Jane, Hash.
THC detection varies depending on the frequency of use. It is generally detectable in urine for 3–30 days, with chronic users remaining positive for several weeks
The iScreen™ Urine Test Dx Drug Screen Cup (12 Panel) provides a fast, reliable, and convenient solution for preliminary multi-drug screening using a single urine specimen. Capable of detecting 12 commonly abused drugs in approximately 5 minutes, this CLIA-waived device combines specimen collection and testing into one easy-to-use system. The inclusion of Creatinine (CR), pH, and Specific Gravity (SG) validity parameters helps evaluate specimen integrity, increasing confidence in preliminary screening results. Designed for hospitals, clinical laboratories, physician offices, occupational health programs, rehabilitation centers, and workplace drug testing, the iScreen™ Dx Cup offers an efficient and dependable solution for professional point-of-care drug screening. As with all rapid immunoassay screening devices, any preliminary positive result should be confirmed using Gas Chromatography/Mass Spectrometry (GC-MS) or Liquid Chromatography–Mass Spectrometry (LC-MS/MS) before medical, legal, or employment decisions are made.
The iScreen™ Urine Test Dx Drug Screen Cup is a CLIA-waived, self-contained multi-panel urine drug screening device designed to provide fast, accurate, and reliable preliminary detection of 12 commonly abused drugs from a single urine specimen. By combining urine collection and drug screening into one convenient device, the iScreen™ Dx Cup minimizes specimen handling, reduces exposure during collection, and improves testing efficiency for healthcare professionals.
This iScreen™ Dx 12-panel Drug Screen Cup delivers qualitative preliminary results in approximately 5 minutes using advanced lateral flow chromatographic immunoassay technology. It is designed for professional point-of-care testing in hospitals, physician offices, clinical laboratories, occupational health clinics, rehabilitation centers, correctional facilities, and workplace drug testing programs.
In addition to screening for multiple drugs of abuse, this configuration also includes urine specimen validity parameters for Creatinine (CR), pH, and Specific Gravity (SG). These additional indicators help assess specimen integrity by identifying diluted or abnormal urine samples, improving confidence in the preliminary screening results.
Available in both round and square cup formats, the iScreen™ Dx Cup provides a hygienic, convenient, and reliable solution for rapid urine drug testing in professional healthcare and occupational settings
This 12-Panel configuration screens for the following drug analytes:
This configuration also evaluates the following urine specimen validity parameters:
Drug
Typical Detection Window
Amphetamine (AMP)
1–3 Days
Barbiturates (BAR)
2–15 Days
Benzodiazepines (BZO)
2–7 Days*
Buprenorphine (BUP)
3–7 Days
Cocaine (COC)
2–4 Days
Methamphetamine (MET)
2–4 Days
MDMA
2–4 Days
Methadone (MTD)
3–7 Days
Opiates (OPI)
2–3 Days
Oxycodone (OXY)
2–4 Days
Phencyclidine (PCP)
5–8 Days
Marijuana (THC)
3–30 Days
*Long-acting benzodiazepines may remain detectable for a longer period
A colored line appears in both the Control (C) region and the Test (T) region for each drug being tested. Even a faint line in the Test (T) region should be interpreted as a negative result.
Only one colored line appears in the Control (C) region, while no line appears in the Test (T) region for the corresponding drug. This indicates that the drug concentration may be at or above the screening cutoff level. Any preliminary positive result should be confirmed using Gas Chromatography/Mass Spectrometry (GC-MS) or Liquid Chromatography–Mass Spectrometry (LC-MS/MS).
If no Control (C) line appears, the test is invalid regardless of whether a Test line appears. Repeat the test using a new device and a fresh urine specimen

iScreen™ Urine Test Dx Drug Screen Cup (12 Panel) | Abbott | Amphetamine, Barbiturates. Benzodiazepines, Buprenorphine, Cocaine, Methamphetamine, MDMA (Ecstasy) Methadone, Opiates, Oxycodone, Phencyclidine, Marijuana | ABTDUAW112702B 25/Box
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